“The diagnosis of LP carries significant controversy regarding its surgical management.
Lymph node involvement is almost always present at the time of diagnosis, and due to its
diffuse nature, microscopic disease is often found at the resection margins. Peritoneal
dissemination is frequently encountered at the time of surgery or as the main site of
recurrence. As such, curative resection is possible in less than half of patients and early
recurrence is common, leading to a dismal median survival, ranging from 6 to 12 months,
and 5-year survival between 8 and 13 %.”

“Whereas outcomes in these earlier studies were discouraging, more recent focus has
identified several prognostic factors that could be used to select patients who benefit from
surgical treatment. Complete surgical resection (R0) has consistently been associated with
improved survival in LP patients. Pedrazzani et al. reported a median OS of 16 months
in patients who underwent R0 gastrectomy compared with 5.2 months in patients who
received an R1 resection (defined as positive margins or positive peritoneal cytology) and
2.8 months in patients deemed unresectable at the time of surgery (
p < 0.001).”

Blackham AU, et al . Is Linitis Plastica a Contraindication for Surgical Resection: A Multi-Institution Study of the U.S. Gastric Cancer Collaborative. Ann Surg Oncol. 2016 Apr;23(4):1203-11. Free Full Text