Essential Articles for Surgical Residents

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We are excited to share a new section titled “Essential Articles for Surgical Residents.”

Keeping up with surgical literature in residency can be challenging. This list was created to serve as an easily accessible, up-to-date, and evidence-based resource for residents.

The content has been curated by faculty from each department and is intended to supplement the standard educational curriculum of each rotation with current and relevant literature.

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Watchful Waiting for men with minimally symptomatic inguinal hernia. (Original 2006 study and 2013 follow up.)

2013

“Annually, more than 20 million inguinal herniorrhaphies are performed worldwide, and it is one of the most common operations performed by general surgeons. Up to one third of patients with inguinal hernias are asymptomatic or minimally symptomatic at the time of presentation. Historically, surgeons have recommended repair of an inguinal hernia at diagnosis even if minimally symptomatic to avoid a hernia accident, which is defined as a bowel obstruction caused by the hernia or strangulation of the contents of the hernia, or both. However, on the basis of the results of 2 recent randomized clinical trials (RCTs), one conducted in the United Kingdom and the other in North America, watchful waiting (WW) has now become an accepted alternative to routine repair. In 2011, the longer-term
results of the United Kingdom trial were published. Using Kaplan-Meier analysis, 72% of patients were predicted to crossover (CO) from WW to surgery by 7.5 years causing the authors to conclude that routine repair should be recommended for minimally symptomatic
patients without medical contraindications to surgery.”

“The results of this study show that WW remains a safe strategy even on long-term follow-up. However, patients who present to their physicians to have the hernia evaluated, especially if they are elderly, should be informed that they will almost certainly come to
surgery eventually. These results should not be extrapolated to the broader population of all patients with asymptomatic or minimally symptomatic hernias.”

Fitzgibbons, Robert J Jr et al. “Long-term results of a randomized controlled trial of a nonoperative strategy (watchful waiting) for men with minimally symptomatic inguinal hernias.Annals of surgery vol. 258,3 (2013): 508-15. Full Text for Emory Users

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Postoperative bleeding after complex abdominal wall reconstruction

“Rates of postoperative bleeding and transfusion are either widely variable or often unreported. As a high-volume center, we have anecdotally appreciated significant rates of each but admittedly have not accurately reported the degree of this specific morbidity in
our practice. This study aims to quantify postoperative blood loss, rates of blood transfusion, and the incidence of operative or endovascular intervention for bleeding, as well as associated risk factors contributing to this morbidity in patients undergoing open TAR.”

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Selection of pancreaticojejunostomy technique after pancreaticoduodenectomy: duct-to-mucosa anastomosis is not better than invagination anastomosis

“Pancreaticoduodenectomy (PD) is a complex, high-risk standard surgical procedure that is indicated primarily for periampullary diseases. Central to the entire discipline of PD are postoperative mortality and morbidity. Although operative mortality in patients undergoing PD has decreased, the incidence of postoperative morbidity remains high at 40% to 50%. Postoperative pancreatic fistula (POPF) is the most common complication, with rates ranging from 5% to 30% in previous studies. Many methods have been described to decrease the risk of POPF, including the use of medications (prophylactic octreotide, sealants), prophylactic pancreatic stenting, and improvements in pancreatic reconstruction techniques. The most commonly used pancreatic reconstruction techniques are pancreaticogastrostomy (PG) and pancreaticojejunostomy (PJ).”

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Occlusion of the Pancreatic Duct Versus Pancreaticojejunostomy

“Pancreatic fistulas and pancreatitis may develop in the pancreatic remnant and may lead to hemorrhage, sepsis, and subsequent death. Procedures to avoid pancreaticojejunostomy were described, including total pancreatectomy. None of these has so far proven to diminish morbidity significantly. Another technique investigated is obliteration closure of the pancreatic duct with a chemical substance, thus avoiding a pancreaticojejunostomy. This method was proposed by Gebhardt et al. They studied the effect of occlusion of the pancreatic duct system with Ethibloc, an alcoholic prolamine, in animal experiments. The pancreatic duct may also be occluded with a fibrin glue solution, Tissucol, which was found to have a more protective effect on beta cell function than the other solutions used.”

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Pancreatic fistula following pancreatoduodenectomy. Evaluation of different surgical approaches in the management of pancreatic stump.

“Pancreatoduodenectomy (PD) is the gold standard surgical procedure performed for both benign and malignant diseases of the pancreas and periampullary region. Since the introduction of PD by Whipple in 1941, the treatment of the pancreatic stump was felt as
primary issue due to the frequency of the complications. Advances in medical and surgical care have made the mortality rate after PD declined dramatically (0e5%), even in centres with experienced surgeons. However, the morbidity rate remains quite high, approaching the 50%. The most common complications after PD are pancreatic fistula, late gastric empty, haemorrhage, hepatic-jejunostomy leakage, wound infection and intraabdominal abscess, which affect mortality rate, hospitalization and costs. At present, pancreatic fistula (PF) is the most significant complication, with a rate ranges from 5% to 40% even in tertiary centers. About the 40% of the patient deaths are the results of septic and haemorrhagic complication following PF. Although, attempting to reduce complications, many refinements of the cur-
rent surgical techniques, pancreatico-jejunostomy, pancreaticogastrostomy and duct occlusion, have been proposed. Nevertheless, the best method to manage the pancreatic stump is still debated.”

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Preoperative Nutrition Status and Postoperative Outcomesin Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

“Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is complex surgery to treat peritoneal surface malignancy (PSM). PSM arises from gastrointestinal (GI), gynecological, or primary peritoneal cancers. CRS aims to completely remove macroscopic tumor. In order to achieve complete cytoreduction, multiple abdominal organ resections are often necessary. After cytoreduction, HIPEC is delivered into the abdominal cavity for 30–90 min to treat residual microscopic disease.”
“Malnutrition is prevalent in patients undergoing surgery for abdominopelvic malignancy and is associated with increased morbidity, longer hospital length of stay (LOS), and mortality. Preoperative malnutrition is a risk factor for organ dysfunction, impaired immune function,
wound complications, impaired physical function, and increased LOS. Malnutrition prevalence is documented in up to 67% of patients with ovarian cancer and 30–50% of patients with colorectal cancer.”

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Air Embolism: Diagnosis, Clinical Management and Outcomes

“Air embolism is a rare but potentially fatal complication of surgical procedures. Rapid
recognition and intervention is critical for reducing morbidity and mortality.”

“Iatrogenic procedures are the main cause of vascular air embolism (VAE). This rare complication can arise in a wide range of clinical scenarios involving line placement, trauma, barotrauma, and several types of surgical procedures including cardiac, vascular, and neurosurgery. Traditionally, surgery and trauma were the most significant causes of systemic and cerebral air embolism; however, endoscopy, angiography, tissue biopsy, thoracocentesis, hemodialysis, and central/peripheral venous access now comprise a greater proportion. The insertion and maintenance of advanced vascular
access devices are increasingly being performed within multiple clinical specialties. Moreover, the bulk of interventional radiology (IR) procedures commence with the placement of an intravascular sheath, which is a major risk factor for air embolism throughout the duration of the procedure. Endovascular procedures complicated by an intravascular air embolism result in significant morbidity and mortality.
VAE is a potentially preventable condition, which arises as a result of a pressure gradient that allows air to enter the blood stream, which can subsequently cause blockages in blood flow. VAE has an estimated incidence of 1 in 772 according to one series, while another study found that the incidence of iatrogenic gas embolism complicates 2.65 per 100,000 hospitalizations; however, these figures are considered lower than the true incidence due to many unreported instances and undiagnosed asymptomatic patients.”

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