HEPATOBILIARY SURGERY

TopicArticles
Gallbladder Cancer Butte JM, et al. Residual disease predicts outcomes after definitive resection for incidental gallbladder cancer. J Am Coll Surg. 2014 Sep;219(3):416-29. doi: 10.1016/j.jamcollsurg.2014.01.069. PMID: 25087941.  

D’Angelica M, et al. Analysis of the extent of resection for adenocarcinoma of the gallbladder. Ann Surg Oncol. 2009 Apr;16(4):806-16. doi: 10.1245/s10434-008-0189-3. PMID: 18985272.  

Ethun CG, Postlewait LM, Le N, Pawlik TM, Buettner S, Poultsides G, Tran T, Idrees K, Isom CA, Fields RC, Jin LX, Weber SM, Salem A, Martin RC, Scoggins C, Shen P, Mogal HD, Schmidt C, Beal E, Hatzaras I, Shenoy R, Merchant N, Cardona K, Maithel SK. A Novel Pathology-Based Preoperative Risk Score to Predict Locoregional Residual and Distant Disease and Survival for Incidental Gallbladder Cancer: A 10-Institution Study from the U.S. Extrahepatic Biliary Malignancy Consortium. Ann Surg Oncol. 2017 May;24(5):1343-1350. doi: 10.1245/s10434-016-5637-x. PMID: 27812827.  

Ethun CG, Postlewait LM, Le N, Pawlik TM, Buettner S, Poultsides G, Tran T, Idrees K, Isom CA, Fields RC, Jin LX, Weber SM, Salem A, Martin RC, Scoggins C, Shen P, Mogal HD, Schmidt C, Beal E, Hatzaras I, Shenoy R, Kooby DA, Maithel SK. Association of Optimal Time Interval to Re-resection for Incidental Gallbladder Cancer With Overall Survival: A Multi-Institution Analysis From the US Extrahepatic Biliary Malignancy Consortium. JAMA Surg. 2017 Feb 1;152(2):143-149. doi: 10.1001/jamasurg.2016.3642. PMID: 27784058.  

Ethun CG, Postlewait LM, Le N, Pawlik TM, Poultsides G, Tran T, Idrees K, Isom CA, Fields RC, Krasnick BA, Weber SM, Salem A, Martin RCG, Scoggins CR, Shen P, Mogal HD, Schmidt C, Beal E, Hatzaras I, Shenoy R, Cardona K, Maithel SK. Routine port-site excision in incidentally discovered gallbladder cancer is not associated with improved survival: A multi-institution analysis from the US Extrahepatic Biliary Malignancy Consortium. J Surg Oncol. 2017 Jun;115(7):805-811. doi: 10.1002/jso.24591. PMID: 28230242.  

Gamboa AC, Maithel SK. The Landmark Series: Gallbladder Cancer. Ann Surg Oncol. 2020 Aug;27(8):2846-2858.

Primrose JN, et al. Capecitabine compared with observation in resected biliary tract cancer (BILCAP): a randomised, controlled, multicentre, phase 3 study. Lancet Oncol. 2019 May;20(5):663-673. doi: 10.1016/S1470-2045(18)30915-X. Epub 2019 Mar 25. Erratum in: Lancet Oncol. 2019 Apr 2;: PMID: 30922733.  
CholangiocarcinomaBrindley PJ, et al. Cholangiocarcinoma. Nat Rev Dis Primers. 2021 Sep 9;7(1):65. doi: 10.1038/s41572-021-00300-2. PMID: 34504109.  

Cloyd JM, Ejaz A, Pawlik TM. The Landmark Series: Intrahepatic Cholangiocarcinoma. Ann Surg Oncol. 2020 Aug;27(8):2859-2865.

Maithel SK, Gamblin TC, Kamel I, Corona-Villalobos CP, Thomas M, Pawlik TM. Multidisciplinary approaches to intrahepatic cholangiocarcinoma. Cancer. 2013 Nov 15;119(22):3929-42. doi: 10.1002/cncr.28312. PMID: 23963845.  

Rea DJ, et al. Liver transplantation with neoadjuvant chemoradiation is more effective than resection for hilar cholangiocarcinoma. Ann Surg. 2005 Sep;242(3):451-8; discussion 458-61. doi: 10.1097/01.sla.0000179678.13285.fa. PMID: 16135931.  

Rocha FG, et al. Hilar cholangiocarcinoma: the Memorial Sloan-Kettering Cancer Center experience. J Hepatobiliary Pancreat Sci. 2010 Jul;17(4):490-6. doi: 10.1007/s00534-009-0205-4. PMID: 19806295.  

Soares KC, Jarnagin WR. The Landmark Series: Hilar Cholangiocarcinoma. Ann Surg Oncol. 2021 Aug;28(8):4158-4170. doi: 10.1245/s10434-021-09871-6. PMID: 33829358; PMCID: PMC9273057.  

Tao R, et al. Ablative Radiotherapy Doses Lead to a Substantial Prolongation of Survival in Patients With Inoperable Intrahepatic Cholangiocarcinoma: A Retrospective Dose Response Analysis. J Clin Oncol. 2016 Jan 20;34(3):219-26. doi: 10.1200/JCO.2015.61.3778. Erratum in: J Clin Oncol. 2019 Apr 10;37(11):942. PMID: 26503201.
Benign Liver Tumors 
Hepatocellular CarcinomaCheng AL, et al. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol. 2009 Jan;10(1):25-34. doi: 10.1016/S1470-2045(08)70285-7. PMID: 19095497.
 
Finn RS, et al.; IMbrave150 Investigators. Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma. N Engl J Med. 2020 May 14;382(20):1894-1905. doi: 10.1056/NEJMoa1915745. PMID: 32402160.
 
Llovet JM, et al. Hepatocellular carcinoma. Nat Rev Dis Primers. 2021 Jan 21;7(1):6. doi: 10.1038/s41572-020-00240-3. PMID: 33479224.
 
Llovet JM, et al.; SHARP Investigators Study Group. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med. 2008 Jul 24;359(4):378-90. doi: 10.1056/NEJMoa0708857. PMID: 18650514.
 
Mazzaferro V, et al. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med. 1996 Mar 14;334(11):693-9. doi: 10.1056/NEJM199603143341104. PMID: 8594428.
Liver MetastasesGangi A, Howe JR. The Landmark Series: Neuroendocrine Tumor Liver Metastases. Ann Surg Oncol. 2020 Sep;27(9):3270-3280. doi: 10.1245/s10434-020-08787-x. PMID: 32632880; PMCID: PMC7415723.

Kawaguchi Y, Vauthey JN. The Landmark Series: RCTs Examining Perioperative Chemotherapy and Postoperative Adjuvant Chemotherapy for Resectable Colorectal Liver Metastasis. Ann Surg Oncol. 2020 Oct;27(11):4263-4270. doi: 10.1245/s10434-020-08809-8. PMID: 32642998.  
Pancreatic AdenocarcinomaDillhoff M, Pawlik TM. Role of Node Dissection in Pancreatic Tumor Resection. Ann Surg Oncol. 2021 Apr;28(4):2374-2381. See also: ASO Author Reflections: Role of Node Dissection in Pancreatic Tumor Resection.
 
He J, et al. Landmark Series: Neoadjuvant Treatment in Borderline Resectable Pancreatic Cancer. Ann Surg Oncol. 2021 Mar;28(3):1514-1520.
 
Rocha FG. Landmark Series: Immunotherapy and Targeted Therapy for Pancreatic Cancer. Ann Surg Oncol. 2021 Mar;28(3):1400-1406. doi: 10.1245/s10434-020-09367-9. PMID: 33386541.
 
Sachs TE, Tseng JF. Landmark Series in Pancreatic Tumors: Anastomotic Techniques and Route of Reconstruction. Ann Surg Oncol. 2021 Apr;28(4):2227-2234.
 
Shah MM, Datta J, Merchant NB, Kooby DA. Landmark Series: Importance of Pancreatic Resection Margins. Ann Surg Oncol. 2022 Mar;29(3):1542-1550. doi: 10.1245/s10434-021-11168-7. PMID: 34985731.
 
van Hilst J, et al. The Landmark Series: Minimally Invasive Pancreatic Resection. Ann Surg Oncol. 2021 Mar;28(3):1447-1456. doi: 10.1245/s10434-020-09335-3. PMID: 33341916; PMCID: PMC7892688.
 
White RR, Murphy JD, Martin RCG. The Landmark Series: Locally Advanced Pancreatic Cancer and Ablative Therapy Options. Ann Surg Oncol. 2021 Aug;28(8):4173-4180.
Non-PDAC Masses
of the Pancreas
Tanaka M, et al. Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas. Pancreatology. 2017 Sep-Oct;17(5):738-753. doi: 10.1016/j.pan.2017.07.007. PMID: 28735806.
Chronic Pancreatitis
Bile Duct Injury
Choledochal Cysts
Gastric CancerAl-Batran SE, et al.; FLOT4-AIO Investigators. Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial. Lancet. 2019 May 11;393(10184):1948-1957. doi: 10.1016/S0140-6736(18)32557-1. PMID: 30982686.

Cunningham D, et al., MAGIC Trial Participants. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Engl J Med. 2006 Jul 6;355(1):11-20. doi: 10.1056/NEJMoa055531. PMID: 16822992.

Dineen SP, Pimiento JM. The Landmark Series: Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS/HIPEC) for Treatment of Gastric Cancer Metastatic to Peritoneum. Ann Surg Oncol. 2021 Aug;28(8):4130-4137.

Ng SP, Leong T. Role of Radiation Therapy in Gastric Cancer. Ann Surg Oncol. 2021 Aug;28(8):4151-4157.
GISTKeung EZ, et al. The Landmark Series: Systemic Therapy for Resectable Gastrointestinal Stromal Tumors. Ann Surg Oncol. 2020 Oct;27(10):3659-3671.

EUH SURGERY B/EUHM/ ESJH GENERAL SURGERY

TopicArticles
Anti-Reflux & Gastroparesis SurgeryBroeders JA, et al. Systematic review and meta-analysis of laparoscopic Nissen (posterior total) versus Toupet (posterior partial) fundoplication for gastro-oesophageal reflux disease. Br J Surg. 2010 Sep;97(9):1318-30. doi: 10.1002/bjs.7174. PMID: 20641062.

Galmiche JP, et al. Laparoscopic antireflux surgery vs esomeprazole treatment for chronic GERD: the LOTUS randomized clinical trial. JAMA. 2011 May 18;305(19):1969-77. doi: 10.1001/jama.2011.626. PMID: 21586712.  

Jobe BA, et al. Preoperative diagnostic workup before antireflux surgery: an evidence and experience-based consensus of the Esophageal Diagnostic Advisory Panel. J Am Coll Surg. 2013 Oct;217(4):586-97. doi: 10.1016/j.jamcollsurg.2013.05.023. PMID: 23973101.

Rodriguez J, et al. Per-oral Pyloromyotomy (POP) for Medically Refractory Gastroparesis: Short Term Results From the First 100 Patients at a High Volume Center. Ann Surg. 2018 Sep;268(3):421-430. doi: 10.1097/SLA.0000000000002927. PMID: 30004920.

van der Westhuizen L, et al. The need for fundoplication at the time of laparoscopic paraesophageal hernia repair. Am Surg. 2013 Jun;79(6):572-7. PMID: 23711265.
Bariatric SurgeryYeung KTD, et al. Does Sleeve Gastrectomy Expose the Distal Esophagus to Severe Reflux?: A Systematic Review and Meta-analysis. Ann Surg. 2020 Feb;271(2):257-265. doi: 10.1097/SLA.0000000000003275. PMID: 30921053.
Benign Foregut Surgery 
Complex Abdominal Wall Reconstruction 
HerniasBelyansky I, et al. A novel approach using the enhanced-view totally extraperitoneal (eTEP) technique for laparoscopic retromuscular hernia repair. Surg Endosc. 2018 Mar;32(3):1525-1532. doi: 10.1007/s00464-017-5840-2. PMID: 28916960.

Daes J, Felix E. Critical View of the Myopectineal Orifice. Ann Surg. 2017 Jul;266(1):e1-e2. doi: 10.1097/SLA.0000000000002104. PMID: 27984213

Deerenberg EB, et al. Small bites versus large bites for closure of abdominal midline incisions (STITCH): a double-blind, multicentre, randomised controlled trial. Lancet. 2015 Sep 26;386(10000):1254-1260.

Fitzgibbons RJ Jr, et al.; Investigators of the Original Trial. Long-term results of a randomized controlled trial of a nonoperative strategy (watchful waiting) for men with minimally symptomatic inguinal hernias. Ann Surg. 2013 Sep;258(3):508-15. doi: 10.1097/SLA.0b013e3182a19725. PMID: 24022443.

Petro CC, et al. Robotic vs Laparoscopic Ventral Hernia Repair with Intraperitoneal Mesh: 1-Year Exploratory Outcomes of the PROVE-IT Randomized Clinical Trial. J Am Coll Surg. 2022 Jun 1;234(6):1160-1165. doi: 10.1097/XCS.0000000000000171. PMID: 35703814.    

El-Tamer “A schematic model for teaching groin hernia surgery” Surg Rounds 2000. Unable to locate citation.

Antoniou SA, et al European Hernia Society guidelines on prevention and treatment of parastomal hernias. Hernia. 2018 Feb;22(1):183-198.

EUH Surgery A

TOPICARTICLES
Portal HTNMillikan WJ Jr, et al. The Emory prospective randomized trial: selective versus nonselective shunt to control variceal bleeding. Ten year follow-up. Ann Surg. 1985 Jun;201(6):712-22. doi: 10.1097/00000658-198506000-00007. PMID: 3890781; PMCID: PMC1250801.
 
Salam AA, et al. Hemodynamic contrasts between selective and total portal-systemic decompression. Ann Surg. 1971 May;173(5):827-44. doi: 10.1097/00000658-197105000-00022. PMID: 4933303; PMCID: PMC1397510.
 
Wong M, Busuttil RW. Surgery in Patients with Portal Hypertension. Clin Liver Dis. 2019 Nov;23(4):755-780. doi: 10.1016/j.cld.2019.07.003. PMID: 31563221.
Non-HPB Cirrhosis General Surgery Endale Simegn A, et al. Perioperative management of patients with liver disease for non-hepatic surgery: A systematic review. Ann Med Surg (Lond). 2022 Feb 24;75:103397. doi: 10.1016/j.amsu.2022.103397. PMID: 35242334; PMCID: PMC8886011.

Johnson KM, et al. Incidence and Risk Factors of Postoperative Mortality and Morbidity After Elective Versus Emergent Abdominal Surgery in a National Sample of 8193 Patients With Cirrhosis. Ann Surg. 2021 Oct 1;274(4):e345-e354. doi: 10.1097/SLA.0000000000003674. PMID: 31714310.

Neeff HP, et al. Early mortality and long-term survival after abdominal surgery in patients with liver cirrhosis. Surgery. 2014 Apr;155(4):623-32. doi: 10.1016/j.surg.2013.11.009. PMID: 24468037.

Theruvath TP, Adams DB. Preoperative transjugular intrahepatic portosystemic shunt for extrahepatic surgery in cirrhosis. Am Surg. 2010 Jan;76(1):115-7. PMID: 20135955.
ECF & Surgical NutritionBoullata JI, et al. ASPEN Safe Practices for Enteral Nutrition Therapy [Formula: see text]. JPEN J Parenter Enteral Nutr. 2017 Jan;41(1):15-103. doi: 10.1177/0148607116673053. PMID: 27815525.

Compher C, et al. Guidelines for the provision of nutrition support therapy in the adult critically ill patient: The American Society for Parenteral and Enteral Nutrition. JPEN J Parenter Enteral Nutr. 2022 Jan;46(1):12-41. doi: 10.1002/jpen.2267. Erratum in: JPEN J Parenter Enteral Nutr. 2022 Jun 19;: PMID: 34784064.

Owen RM, Love TP, Perez SD, Srinivasan JK, Sharma J, Pollock JD, Haack CI, Sweeney JF, Galloway JR. Definitive surgical treatment of enterocutaneous fistula: outcomes of a 23-year experience. JAMA Surg. 2013 Feb;148(2):118-26. doi: 10.1001/2013.jamasurg.153. PMID: 23560282
Inflammatory Bowel DiseaseBan KA, et al. Effect of Diagnosis on Outcomes in the Setting of Enhanced Recovery Protocols. Dis Colon Rectum. 2018 Jul;61(7):847-853. doi: 10.1097/DCR.0000000000001102. PMID: 29878952.
 
Braga Neto MB, et al. Impact of Bariatric Surgery on the Long-term Disease Course of Inflammatory Bowel Disease. Inflamm Bowel Dis. 2020 Jun 18;26(7):1089-1097. doi: 10.1093/ibd/izz236. PMID: 31613968; PMCID: PMC7534455.

Hanauer SB, et al.; ACCENT I Study Group. Maintenance infliximab for Crohn’s disease: the ACCENT I randomised trial. Lancet. 2002 May 4;359(9317):1541-9. doi: 10.1016/S0140-6736(02)08512-4. PMID: 12047962.
 
Lowe SC, et al. Declining Rates of Surgery for Inflammatory Bowel Disease in the Era of Biologic Therapy. J Gastrointest Surg. 2021 Jan;25(1):211-219. doi: 10.1007/s11605-020-04832-y. PMID: 33140318.

Kline BP, et al. Clinical and Genetic Factors Impact Time to Surgical Recurrence After Ileocolectomy for Crohn’s Disease. Ann Surg. 2021 Aug 1;274(2):346-351. doi: 10.1097/SLA.0000000000003660. PMID: 31714311.
 
Myrelid P, Kalman TD. Old, New, and Out of the Box in IBD Surgery: Proceedings of the European Crohn’s and Colitis Organisation 2020 Congress from a Surgical Perspective. Dis Colon Rectum. 2021 Aug 1;64(8):929-931. doi: 10.1097/DCR.0000000000002102. PMID: 33872289

Reinisch W, et al. Long-term infliximab maintenance therapy for ulcerative colitis: the ACT-1 and -2 extension studies. Inflamm Bowel Dis. 2012 Feb;18(2):201-11. doi: 10.1002/ibd.21697. PMID: 21484965.

Cirrhotic nutritional management

“Prevalence of malnutrition in chronic liver disease ranges between 10% and 100%, depends on severity of liver disease. Prevalence is more in patients with alcoholic cirrhosis compared to nonalcoholic cirrhotics. 3 Malnutrition is seen in all clinical stages but is easier to detect in advanced stages of liver cirrhosis. Many patients have subtle changes such as fat soluble vitamin deficiency, anemia from iron, folate or pyridoxine deficiency, altered cell-mediated immune functions and minimal loss of muscle mass, while patients with end-stage liver disease have muscle wasting, decreased fat stores, and cachexia.”

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Vascular injury in hernia repair

“Complications are known to occur at each and every step of hernia surgery. Applying caution while performing each step can save the patient from a lot of morbidity. One starts by applying strict patient selection criteria for endoscopic hernia repair, especially in the initial part of ones learning curve. A thorough knowledge of anatomy goes a long way in avoiding most of the complications seen in hernia repair. This anatomy needs to be relearned from what one is used to, as the approach is totally different from an open hernia repair. And finally, learning and mastering the right technique is an essential prerequisite before one ventures into inguinal hernia repair.”

“The most important preoperative precaution is proper patient selection prior to surgery, especially in the initial part of the learning curve. Ideally, direct or small indirect hernias are best. Large hernias, obese patients and irreducible, obstructed hernias are best avoided. An absolute contraindication is strangulated hernia. Also a detailed work-up of elderly patients to assess cardiorespiratory status is mandatory to ensure a safe outcome.”

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Splenic injury grades & management

“Management of blunt spleen injuries has evolved from mandatory splenectomy to non-operative management (NOM) allowing for splenic salvage. The Eastern Association for the Surgery of Trauma (EAST) practice management guideline for the management of blunt solid organ injury recommends NOM in splenic injury regardless of age, grade, or associated injuries.”

“Splenectomy continues to be the treatment of choice in patients with unstable hemodynamics and a known splenic injury. In the hemodynamically normal patient, current practice is to observe the patient and treat with NOM to save the patients the complications associated with surgery.”

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Parkinson’s Gut Motility

“Growing evidence suggests an increasing significance for the extent of gastrointestinal tract (GIT) dysfunction in Parkinson’s disease (PD). Most patients suffer from GIT symptoms, including dysphagia, sialorrhea, bloating, nausea, vomiting, gastroparesis, and constipation during the disease course. The underlying pathomechanisms of this α-synucleinopathy play an important role in disease development and progression, i.e., early accumulation of Lewy pathology in the enteric and central nervous systems is implicated in pharyngeal discoordination, esophageal and gastric motility/peristalsis impairment, chronic pain, altered intestinal permeability and autonomic dysfunction of the colon, with subsequent constipation.”

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