Management of leakage and fistulas after bariatric surgery

“Leaks and fistulas are among the most feared complications of bariatric surgery. Variable in presentation, acuity, and severity, these often require multimodal and multispecialty management strategies for optimal outcomes. Recent advancements in the realm of endoscopic therapies have made these integral to the treatment algorithm of post-operative leaks and fistulas. In this review, we will discuss the epidemiology, pathophysiology and classification of post-bariatric surgery defects and provide an in-depth assessment of current management strategies, with a focus on endoscopic therapies.”

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Preoperative inspiratory muscle training for postoperative pulmonary complications in adults undergoing cardiac and major abdominal surgery

“Despite advances in perioperative care in the last few decades, postoperative pulmonary complications (PPCs) are probably the leading cause of morbidity and mortality in adults undergoing chest and abdominal surgery. PPCs and cardiac complications are commonly regarded as the two major causes of perioperative problems in selected groups of patients undergoing these high-risk surgical procedures. However, PPCs are more common than postoperative cardiac complications and play a bigger role in mortality and healthcare costs. Despite these factors, the natural history of PPCs and the necessity of preventive strategies have not been well recognized in studies to date.”

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Risk Factors for Chronic Pain after Open Ventral Hernia Repair by Underlay Mesh Placement

“Incisional hernia is one of the most frequent long-term complications after abdominal surgery (11%–20%). After primary repair, rates of recurrence range from 24% to 54%. It has been clearly demonstrated that the use of prostheses for a tension-free repair allows for a
significant reduction in recurrence rate, and even for the treatment of small defects. However, the type and position of the mesh and the mesh fixation technique used are still a matter of debate. The underlay position of the mesh allows for easy treatment of major parietal defects with limited dissection and potentially lower rates of mesh infection, but this position exposes the patient to the risk of small bowel occlusion and enterocutaneous fistula.”

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Inadvertent Enterotomy in Minimally Invasive Abdominal Surgery

“Inadvertent enterotomy (IE) is one of the underreported complications in abdominal surgery. Krabben et al reported a 19% incidence of IE in patients who had a repeat
laparotomy. The incidence of and risk factors for IE during enterolysis were reported in a cohort of patients reoperated on. According to Krabben et al, the risk of inadvertent enterotomy in open surgery is more than 10-fold in patients with a history of 3 or more previous laparotomies.”

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Noninvasive positive pressure ventilation for acute respiratory failure following upper abdominal surgery

“More than four million abdominal surgeries are performed in the US every year and in England about 250,000 abdominal operations are performed per year. Adults undergoing upper abdominal surgery are at an increased risk of postoperative pulmonary complications.
Acute respiratory failure is a relatively common complication after abdominal surgery and is associated with significant morbidity and mortality. According to Michelet 2010, the development of respiratory complication may be explained by two pathological mechanisms.
The first is linked to surgical complications, notably with the occurrence of anastomotic leakage leading to mediastinitis, septic shock, and acute respiratory distress. The second is of medical origin, with multifactorial impairment of respiratory function.”

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Postoperative CD4 counts predict anastomotic leaks in patients withpenetrating abdominal trauma

“Survival following penetrating abdominal trauma has improved significantly, nonetheless despite enhanced resuscitation and surgical intervention strategies the immune mediated systemic inflammatory response syndrome (SIRS) continues to result in organ dysfunction and potential death. Posttraumatic lymphopenia or altered cell-mediated immunity as a result of decreased lymphocyte subsets may affect SIRS severity; however in penetrating trauma it is uncertain which factors may result in decreased CD4 counts and whether or not these changes affect postoperative outcomes, in particular anastomotic complications.”

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Abdominal fascia dehiscence: is there a connection to a special microbial spectrum?

“Acute fascia dehiscence (FD) is a threatening complication occurring in 0.4–3.5% of cases after abdominal surgery. Prolonged hospital stay, increased mortality and increased rate of incisional hernias could be following consequences. Several risk factors are controversially discussed. Even though surgical infection is a known, indisputable risk factor, it is still not proven if a special spectrum of pathogens is responsible. In this study, we investigated if a specific spectrum of microbial pathogens is associated with FD.”

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