“The diagnosis of LP carries significant controversy regarding its surgical management.
Lymph node involvement is almost always present at the time of diagnosis, and due to its
diffuse nature, microscopic disease is often found at the resection margins. Peritoneal
dissemination is frequently encountered at the time of surgery or as the main site of
recurrence. As such, curative resection is possible in less than half of patients and early
recurrence is common, leading to a dismal median survival, ranging from 6 to 12 months,
and 5-year survival between 8 and 13 %.”

“Linitis plastica (LP) is a distinct phenotype of gastric cancer. Macroscopically, it is characterized as a thickened stomach, with prominent diffusion of the tumor into the submucosal and muscular layers; microscopically, it is often associated with signet ring cell features and diffuse and scirrhous (referring to the histologic characteristic of abundant stromal cells) histologic types.”